2025년 우수논문

• The Korean Journal of Internal Medicine에 게재되었던 논문 중 2025년 상·하반기 우수논문을 선정하여 해당 저자에게 상장과 상금(각 30만원)을 지급함

상반기

1. Endoscopic features of cytomegalovirus disease of the upper gastrointestinal tract between transplant and non-transplant patients

¹Division of Gastroenterology, Department of Internal Medicine, Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, Korea
²Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
³Department of Gastroenterology, Gangneung Asan Hospital, University of Ulsan College of Medicine, Gangneung, Korea
Yuri Kim^{1, 2}, Do Hoon Kim², Myeongsook Seo³, Hee Kyong Na², Kee Wook Jung², Ji Yong Ahn², Jeong Hoon Lee², Kee Don Choi², Ho June Song², Gin Hyug Lee², Hwoon-Yong Jung²
(Korean J Intern Med 2025;40(3):394-403)

2. Sex-specific impact of the COVID-19 outbreak on the incidence of metabolic syndrome: a comparative study of 2018–2019 and 2020–2021

¹Division of Cardiology, National Health Insurance Service Ilsan Hospital, Goyang, Korea
²Division of Cardiology, Department of Internal Medicine, Hanyang University Guri Hospital, Hanyang University College of Medicine, Guri, Korea
³Department of Precision Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea
⁴Division of Cardiology, Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea
⁵Division of Endocrinology, Department of Internal Medicine, CHA University School of Medicine, Pocheon, Korea
⁶Department of Medical Informatics and Biostatistics, Graduate School, Yonsei University, Wonju, Korea
⁷Division of Cardiology, Department of Internal Medicine, Gachon University Gil Medical Center, Incheon, Korea
Kyeong-Hyeon Chun¹, Hyun-Jin Kim², Dae Ryong Kang³, Jang Young Kim⁴, Wonjin Kim⁵, Yong Whi Jeong⁶, Seung Hwan Han⁷, Kwang Kon Koh⁷and on behalf of the Taskforce Team of the Metabolic Syndrome Fact Sheet of the Korean Society of Cardiometabolic Syndrome
(Korean J Intern Med 2025;40(2):262-274)

3. Impact of tracheostomy on clinical outcomes in ventilated patients with severe pneumonia: a propensity-matched cohort study

¹Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Internal Medicine, Pusan National University Hospital, Busan, Korea
²Department of Internal Medicine, School of Medicine, Pusan National University, Busan, Korea
³Biomedical Research Institute, Pusan National University Hospital, Busan, Korea
Hayoung Seong^{1, 2, 3}, Hyojin Jang^{1, 2, 3}, Wanho Yoo^{1, 2, 3}, Saerom Kim^{1, 2, 3}, Kwangha Lee^{1, 2, 3}
(Korean J Intern Med 2025;40(2):286-298)

4. Persistent influence of past obesity on current adiponectin levels and mortality in patients with type 2 diabetes

¹Department of Internal Medicine, Kyungpook National University Chilgok Hospital, School of Medicine, Kyungpook National University, Daegu, Korea
²Department of Internal Medicine, Daegu Catholic University Hospital, Daegu Catholic University School of Medicine, Daegu, Korea
³Department of Internal Medicine, Kyungpook National University Hospital, School of Medicine, Kyungpook National University, Daegu, Korea
Min-Ji Kim¹, Sung-Woo Kim², Bitna Ha³, Hyang Sook Kim³, So-Hee Kwon¹, Jonghwa Jin³, Yeon-Kyung Choi¹, Keun-Gyu Park³, Jung Guk Kim³, In-Kyu Lee³, Jae-Han Jeon³
(Korean J Intern Med 2025;40(2):299-309)

5. Reduced-intensity chemotherapy with tyrosine kinase inhibitor followed by allogeneic transplantation is effective in patients with Philadelphia chromosome-positive acute lymphoblastic leukemia

¹Department of Hematology/Oncology, Kyungpook National University Hospital, School of Medicine, Kyungpook National University, Daegu, Korea
²Division of Hematology-Oncology, Department of Internal Medicine, Pusan National University Hospital, Pusan National University School of Medicine, Busan, Korea
³Department of Hemato-Oncology, Keimyung University Dongsan Medical Center, Daegu, Korea
⁴Department of Internal Medicine, Yeungnam University Medical Center, Yeungnam University College of Medicine, Daegu, Korea
Jung Min Lee^{1, *}, Do Young Kim^{2, *}, Hee Jeong Cho¹, Joon Ho Moon¹, Sang Kyun Sohn¹, Ho Jin Shin², Young Rok Do³, Mi Hwa Heo³, Min Kyoung Kim⁴, Young Seob Park⁴, Dong Won Baek¹
(Korean J Intern Med 2025;40(1):124-134)

6. Impaired aldosterone response to potassium and hyperkalemia in patients receiving a renin-angiotensin-aldosterone system inhibitor

Division of Nephrology, Department of Internal Medicine, Jeju National University Hospital, Jeju National University, School of Medicine, Jeju, Korea
Miyeon Kim, Hwa Young Lee, Hyunwoo Kim
(Korean J Intern Med 2025;40(3):468-481)

7. Initial and peak serum levels of Krebs von den Lungen-6 for predicting the prognosis of patients with COVID-19

Department of Infectious Diseases, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
Geonui Kim, Hyeonwoo Kwon, Sang Hyun Ra, Euijin Chang, Seongman Bae, Jiwon Jung, Min Jae Kim, Yong Pil Chong, Sang-Oh Lee, Sang-Ho Choi, Yang Soo Kim, Sung-Han Kim
(Korean J Intern Med 2025;40(2):321-329)

8. Comparison of extrafine and non-extrafine inhaled corticosteroids/long-acting β2-agonists as maintenance and reliever therapy in asthma : a randomized open-label crossover trial

¹Division of Pulmonology and Allergy, Department of Internal Medicine, Gachon University Gil Medical Center, Gachon University College of Medicine, Incheon, Korea
²Division of Respiratory Disease and Allergy, Department of Internal Medicine, Dankook University College of Medicine, Cheonan, Korea
Sang Pyo Lee^{1, *}, Sang Min Lee^{2, *}, Sung-Yoon Kang¹
(Korean J Intern Med 2025;40(3):491-501)

9. Clinical perspective on serum periostin in antineutrophil-cytoplasmic antibody-associated vasculitis

¹Department of Medical Science, BK21 Plus Project, Yonsei University College of Medicine, Seoul, Korea
²Division of Rheumatology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea
³Institute for Immunology and Immunological Diseases, Yonsei University College of Medicine, Seoul, Korea
Taejun Yoon^{1, *}, Jiyeol Yoon^{2, *}, Eunhee Ko¹, Yong-Beom Park^{2, 3}, Sang-Won Lee^{2, 3}
(Korean J Intern Med 2025;40(3):512-523)

하반기

1. Prevalence of cholesterol gallstones in a Korean population over a 14-year period

¹Department of Medicine, Chung-Ang University College of Medicine, Seoul, Korea
²Department of Internal Medicine, Chung-Ang University Gwangmyeong Hospital, Gwangmyeong, Korea
³Division of Gastroenterology, Chung-Ang University College of Medicine, Seoul, Korea
⁴Department of Surgery, Chung-Ang University College of Medicine, Seoul, Korea
⁵Division of Gastroenterology, Konkuk University Hospital, Konkuk University School of Medicine, Seoul, Korea
⁶Department of Anesthesiology and Pain Medicine, Chung-Ang University College of Medicine, Seoul, Korea
Gyumin Lee^{1, *}, Jeong Yoon Suh^{1, *}, Junyeol Kim², Tae Young Park^{2, 3}, Jae Hyuk Do³, Yoo Shin Choi⁴, Seung Eun Lee⁴, Tae Yoon Lee⁵, Hyun Kang⁶, Hyoung-Chul Oh³
(Korean J Intern Med 2025;40(4):584-591)

2. Submucosal saline injection and mini-probe endoscopic ultrasound to assess endoscopic resectability of colorectal subepithelial tumors

¹Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
²Department of Internal Medicine, Soonchunhyang University College of Medicine, Seoul, Korea
³Department of Gastroenterology, St. Vincent’s Hospital, College of Medicine, The Catholic University of Korea, Suwon, Korea
⁴Department of Internal Medicine, Daegu Catholic University School of Medicine, Daegu, Korea
⁵Inflammatory Bowel Disease Center, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
⁶Digestive Disease Research Center, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
Jung-Bin Park^{1, 2}, Ji Eun Baek^{1, 3}, June Hwa Bae^{1, 4}, Seung Wook Hong¹, Sung Wook Hwang^{1, 5, 6}, Sang Hyoung Park^{1, 5}, Byong Duk Ye^{1, 5}, Jeong-Sik Byeon¹, Seung-Jae Myung^{1, 6}, Suk-Kyun Yang^{1, 5}, Dong-Hoon Yang^{1, 6}
(Korean J Intern Med 2025;40(4):592-605)

3. Impact of guideline-directed medical therapy on the cardiac or non-cardiac death in acute myocardial infarction

¹Department of Emergency Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
²Sungkyunkwan University School of Medicine, Seoul, Korea
³Department of Internal Medicine, Keimyung University Dongsan Hospital, Daegu, Korea
⁴Department of Internal Medicine, Korea University Guro Hospital, Seoul, Korea
⁵Department of Internal Medicine, Jeju University Hospital, Jeju, Korea
⁶Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea
⁷Department of Internal Medicine, Chonnam National University Hospital, Gwangju, Korea
Jin-Ho Choi¹, Dahee Hyun² Seung Ho Hur³, Seung Woon Rha⁴, Seung Jae Joo⁵, Hyo-Soo Kim⁶, Myung Ho Jeong⁷; on behalf of KAMIR-NIH investigators
(Korean J Intern Med 2025;40(5):780-789)

4. Long-term clinical outcome and risk stratification across stages of cardiovascular-kidney-metabolic syndrome in a nationwide cohort

¹Division of Cardiology, Department of Internal Medicine, Hanyang University College of Medicine, Hanyang University Guri Hospital, Guri, Korea
²Data Science Team, Hanmi Pharm. Co., Ltd, Seoul, Korea
³Division of Cardiology, Department of Internal Medicine, Hanyang University College of Medicine, Hanyang University Seoul Hospital, Seoul, Korea
⁴Division of Endocrinology, Diabetes and Hypertension, Center for Weight Management and Wellness, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA
⁵Division of Cardiology, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea
Hyun-Jin Kim^{1, *}, Byung Sik Kim^{1, *}, Hasung Kim², Jungkuk Lee², Ha Hye Jo³, Dong Wook Kim⁴, Jeong-Hun Shin¹, Ki-Chul Sung⁵
(Korean J Intern Med 2025;40(6):975-989)

5. Effects of adjunctive dobutamine on outcomes among patients with septic shock: a propensity score matching analysis

¹Department of Pulmonary and Critical Care Medicine, Seoul National University Bundang Hospital, Seongnam, Korea
²Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea
³Department of Digital Healthcare, Seoul National University Bundang Hospital, Seongnam, Korea
⁴Department of Critical Care Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
⁵Department of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
⁶Department of Pulmonary, Allergy and Critical Care Medicine, Hallym University Sacred Heart Hospital, Anyang, Korea
Sung Yoon Lim¹, Kyu Jin Lee², Yeonhoon Jang³, Yeon Joo Lee¹, Ryoung-Eun Ko⁴, Gee Young Suh⁴, Dong Kyu Oh⁵, Su Yeon Lee⁵, Mi Hyeon Park⁵, Chae-Man Lim⁵, Sunghoon Park⁶ and on behalf of the Korean Sepsis Alliance (KSA) investigators
(Korean J Intern Med 2025;40(6):990-1001)

6. Comprehensive approaches to diabetes in the elderly: adapting to evolving trends

¹Division of Endocrinology and Metabolism, Department of Internal Medicine, Eunpyeong St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea
²Division of Geriatrics, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea
³Metabolism-Dementia Institute, Yonsei University College of Medicine, Seoul, Korea
⁴Division of Endocrinology and Metabolism, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea
⁵Department of Internal Medicine, National Health Insurance Service Ilsan Hospital, Goyang, Korea
⁶Division of Geriatrics, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
⁷Division of Endocrinology and Metabolism, Department of Internal Medicine, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea
⁸Department of Medical Informatics, College of Medicine, The Catholic University of Korea, Seoul, Korea
Jeongmin Lee^{1, *}, Kwang Joon Kim^{2, *}, Yang Sun Park^{2, 3}, Yong-ho Lee⁴, Kyeong Hye Park⁵, Hee-Won Jung⁶, Bong-Soo Cha⁴, Hun-Sung Kim^{7, 8}, Chang Oh Kim²
(Korean J Intern Med 2025;40(6):1017-1028)

7. Decreased frequency and inflammatory change of FoxP3+ regulatory T cells in immunopathogenesis of human acute graft-versus-host disease

¹Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea
²Department of Hematology-Oncology, Ajou University School of Medicine, Suwon, Korea
Nayeon Seong^{1, 2, *}, Cheongin Yang^{2, *}, Kunye Kwak¹, Ka-Won Kang¹, Yong Park¹, Byung Soo Kim¹, Seong Hyun Jeong², Joon Seong Park², Yoon Seok Choi^{1, 2}
(Korean J Intern Med 2025;40(4):657-666)

8. Factors influencing delayed attainment of low disease activity in rheumatoid arthritis patients continuing targeted therapy

¹Hanyang University Institute for Rheumatology Research, Seoul, Korea
²Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, Korea
³Division of Rheumatology, Department of Internal Medicine, Chonnam National University Medical School and Hospital, Gwangju, Korea
⁴Department of Rheumatology, Hanyang University Guri Hospital, Hanyang University School of Medicine, Guri, Korea
⁵Division of Rheumatology, Department of Internal Medicine, Catholic University of Daegu School of Medicine, Daegu, Korea
⁶Division of Rheumatology, Department of Internal Medicine, School of Medicine, Kyung Hee University, Seoul, Korea
⁷Division of Rheumatology, Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea
⁸Department of Rheumatology, Ajou University School of Medicine, Suwon, Korea
Yeo-Jin Song¹, Soo-Kyung Cho^{1, 2}, Se Rim Choi^{1, 2}, Shin-Seok Lee³, Hye-Soon Lee⁴, Sung-Hoon Park⁵, Yeon-Ah Lee⁶, Min-Chan Park⁷, Hyoun-Ah Kim⁸, Soo-Bin Lee¹, Ha-Rim Park¹, Eunwoo Nam¹, Yoon-Kyoung Sung^{1, 2}
(Korean J Intern Med 2025;40(5):835-844)

2025년 우수임상화보

• The Korean Journal of Internal Medicine에 투고되었던 임상화보 중 2025년 상·하반기 우수임상화보를 선정하여 상장과 상금(각 30만원)을 지급함

상반기

Acute gouty arthritis of the atlantoaxial joint

¹Division of Rheumatology, Department of Internal Medicine, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea ²Division of Rheumatology, Department of Internal Medicine, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Yangsan, Korea ³Division of Rheumatology, Department of Internal Medicine, Haeundae Paik Hospital, Inje University College of Medicine, Busan, Korea
Su Jin Choi¹, Min Wook So², Sunggun Lee³, Seung Won Choi¹, Doo-Ho Lim¹
(Korean J Intern Med 2025;40(2):341-342)

하반기

Disseminated tuberculosis without pulmonary involvement mimicking multiple bone metastases

Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea
Hyo-Jin Lee, Seo-Jun Byun, Si-Hyun Kim
(Korean J Intern Med 2025;40(6):1068-1069)